Research

The introduction of fluorine atoms into organic compounds is very important in the fields of medicine, agrochemicals, and functional materials. There is a method of synthesizing fluorine-containing organic compounds by using fluorine-containing building blocks, but such compounds are still expensive and limited in quantity, and there is a high need for research and development. In this study, we succeeded in synthesizing fluorine-containing aromatic carboxylic acids with various functional groups from readily available fluorine-containing aromatic compounds and carbon dioxide, and achieved good yields using the organic electrolysis method. The fluorine-containing aromatic carboxylic acids synthesized in this study include a variety of new compounds that are difficult to synthesize by conventional methods, and are expected to be used as promising new fluorine-containing building blocks for the synthesis of pharmaceuticals, agrochemicals, and highly functional materials.