Research

The pump we have developed for liquid chromatography is based on electroosmotic phenomena and can operate for a long time on dry batteries. Since there is no mechanical drive, it is extremely compact and lightweight, and does not generate pulsating flow. Using microfabrication technology, the column and (electrochemical and UV) detectors are mounted on small amounts of substrate, the size of a business card. Conventional packing materials are used for the column, so the same analysis conditions as before can be applied directly without modification. The electrochemical detector uses a uniquely developed comb-shaped electrode. Although small in size, it has comparable sensitivity as conventional detectors. Liquid chromatographs currently used as the main instrument for chemical analysis are large and heavy, limiting their use to specific locations in the laboratory, but the instrument we have developed can easily be used anywhere. The amount of solvent used can also be reduced to 1/100 to 1/1000 of conventional detectors.