Content of research

We have been developing and validating software to objectively measure the progression of joint space narrowing on plain x-rays. The latest software, using our original temporal subtraction and contour extraction techniques, is capable of displaying changes (in square millimeters) in the area of the joint space of the target limb.
On the other hand, even from a global perspective, it is difficult to automatically detect the progression of joint space narrowing on plain x-rays using software, and the process still partially relies on manual operation, making it impossible to perform measurement at individual hospitals or clinics. Therefore, the purpose of this study is to establish an internet-based consulting system for quantitative analysis of destructive changes due to rheumatoid arthritis that can meet the needs of domestic and international clients who lead clinical trials and clinical research.

Potential for social implementation

• By using this system, it will be possible to automatically diagnose rheumatism at hospitals and clinics. It will be an effective tool for pharmaceutical companies to proceed with treatment without delay. Local governments can apply this system to rheumatism screening.

Appealing points to industry and local governments

We aim to diagnose and screen rheumatoid arthritis by using software that can sensitively detect changes in the joint space even in the absence of medical specialists. We will establish the usefulness of this system in cases of advanced rheumatoid arthritis through joint research with pharmaceutical companies. We will also introduce this system to the medical examinations performed by local governments to realize rheumatism screening.