Hokkaido University Research Profiles

Open Facilities

A Single Microscopic Image Can Tell the Whole Story

A Single Microscopic Image Can Tell the Whole Story

The Nikon Imaging Center was established as a facility where researchers throughout Japan can use the latest biological microscopes, and is now operated by the Research Institute for Electronic Science. Our dedicated staff will explain how to operate the equipment and software to beginners who may never have touched a microscope before.

Content of research

Recent years have seen an increasing demand for bioimaging and significant performance improvement in gene transfer technology, molecular and cellular marking technology using fluorescent proteins and observation equipment such as microscopes. However, high performance microscope systems are very expensive, and it is difficult to obtain all the necessary equipment, especially at the start. Another factor that makes imaging technology difficult is the fact that not everyone can easily obtain excellent data
The center’s equipment is made available for researchers outside the university and we not only provide instructions on the operation of the equipment and software, but also technical know-how on imaging. We have also joined the Advanced Bioimaging Support (ABiS) platform from this year, and are involved in supporting the use of cutting-edge microscopes in collaboration with other microscope facilities in Japan. We’d like companies that are exploring the application of imaging to consider the use of our services.

  • Confocal microscope

  • Confocal fluorescence images of cultured cells acquired with a confocal microscope

Potential for social implementation

  • ・Observation with a confocal microscope
  • ・Long-term observation of cell behavior. Good cell condition and focus are maintained for several days
  • ・Non-living samples such as solid substrate surfaces can also be handled.

Appealing points to industry and local governments

Our service is unique in Japan in that it is not only available to universities, but also corporate researchers engaged in research and development. If it is difficult for you to come to Sapporo, our staff will be happy to conduct the observations on your behalf. Please feel free to contact us if you would like to just take a look or give it a try.